Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

<h4>Background</h4> <p>The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipoprotein cholesterol (LDL-C), hi...

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Main Authors: Holzinger, ER, Verma, SS, Moore, CB, Hall, M, De, R, Gilbert-Diamond, D, Lanktree, MB, Pankratz, N, Amuzu, A, Burt, A, Dale, C, Dudek, S, Furlong, CE, Gaunt, TR, Kim, DS, Riess, H, Sivapalaratnam, S, Tragante, V, van Iperen, EPA, Brautbar, A, Carrell, DS, Crosslin, DR, Jarvik, GP, Kuivaniemi, H, Kullo, IJ, Larson, EB, Rasmussen-Torvik, LJ, Tromp, G, Baumert, J, Cruickshanks, KJ, Farrall, M, Hingorani, AD, Hovingh, GK, Kleber, ME, Klein, BE, Klein, R, Koenig, W, Lange, LA, Mӓrz, W, North, KE, Onland-Moret, N, Reiner, AP, Talmud, PJ, van der Schouw, YT, Wilson, JG, Kivimaki, M, Kumari, M, Moore, JH, Drenos, F, Asselbergs, FW, Keating, BJ, Ritchie, MD
Format: Journal article
Language:English
Published: BioMed Central 2017