TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Although there has been much success in identifying genetic variants associated with common diseases using genome-wide association studies (GWAS), it has been difficult to demonstrate which variants are causal and what role they have in disease. Moreover, the modest contribution that these variants...

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Bibliographic Details
Main Authors: Gregory, A, Dendrou, C, Attfield, K, Haghikia, A, Xifara, D, Butter, F, Poschmann, G, Kaur, G, Lambert, L, Leach, O, Prömel, S, Punwani, D, Felce, J, Davis, S, Gold, R, Nielsen, F, Siegel, R, Mann, M, Bell, J, McVean, G, Fugger, L
Format: Journal article
Language:English
Published: 2012