Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection.

Cytotoxic T lymphocytes (CTLs) are thought to play a crucial role in the termination of the acute primary HIV-1 syndrome, but clear evidence for this presumption has been lacking. Here we demonstrate positive selection of HIV-1 proviral sequences encoding variants within a CTL epitope in Nef, a gene...

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Xehetasun bibliografikoak
Egile Nagusiak: Price, D, Goulder, P, Klenerman, P, Sewell, A, Easterbrook, P, Troop, M, Bangham, C, Phillips, R
Formatua: Journal article
Hizkuntza:English
Argitaratua: 1997