SAMHD1-dependent retroviral control and escape in mice

SAMHD1-dependent retroviral control and escape in mice

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SAMHD1 is a host restriction factor for human immunodeficiency virus 1 (HIV-1) in cultured human cells. SAMHD1 mutations cause autoimmune Aicardi-Goutières syndrome and are found in cancers including chronic lymphocytic leukaemia. SAMHD1 is a triphosphohydrolase that depletes the cellular pool of de...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Rehwinkel, J, Maelfait, J, Bridgeman, A, Rigby, R, Hayward, B, Liberatore, R, Bieniasz, P, Towers, G, Moita, L, Crow, Y, Bonthron, D, Reis E Sousa, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2013

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