DUBbing cancer: Deubiquitylating enzymes involved in epigenetics, DNA damage and the cell cycle as therapeutic targets

Controlling cell proliferation is one of the hallmarks of cancer. A number of critical checkpoints ascertain progression through the different stages of the cell cycle, which can be aborted when perturbed, for instance by errors in DNA replication and repair. These molecula...

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Bibliographic Details
Main Authors: Pinto-Fernández, A, Kessler, B
Format: Journal article
Published: Frontiers Media 2016