Complex DNA damage induced by high-LET a-particles and protons triggers a specific cellular DNA damage response
<h4>Purpose</h4> <p>Complex DNA damage (CDD), where two or more DNA lesions are induced in close proximity, is a signature of ionising radiation (IR) that contributes significantly to cell killing due to the difficult nature of its repair. However the precise mechanism of recognit...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Published: |
Elsevier
2017
|