Complex DNA damage induced by high-LET a-particles and protons triggers a specific cellular DNA damage response

Complex DNA damage induced by high-LET a-particles and protons triggers a specific cellular DNA damage response

<h4>Purpose</h4> <p>Complex DNA damage (CDD), where two or more DNA lesions are induced in close proximity, is a signature of ionising radiation (IR) that contributes significantly to cell killing due to the difficult nature of its repair. However the precise mechanism of recognit...

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Bibliographic Details
Main Authors:	Carter, R, Nickson, C, Thompson, J, Kacperek, A, Hill, M, Parsons, J
Format:	Journal article
Published:	Elsevier 2017

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