The surface-exposed PA51-72-loop of the influenza A virus polymerase is required for viral genome replication
The heterotrimeric influenza A virus RNA-dependent RNA polymerase complex, composed of PB1, PB2 and PA subunits, is responsible for transcribing and replicating the viral RNA genome. The N-terminal endonuclease domain of the PA subunit performs endonucleolytic cleavage of capped host RNAs to generat...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
American Society for Microbiology
2018
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