Progress towards a public chemogenomic set for protein kinases and a call for contributions.

Protein kinases are highly tractable targets for drug discovery. However, the biological function and therapeutic potential of the majority of the 500+ human protein kinases remains unknown. We have developed physical and virtual collections of small molecule inhibitors, which we call chemogenomic s...

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Bibliographic Details
Main Authors: Drewry, D, Wells, C, Andrews, D, Angell, R, Al-Ali, H, Axtman, A, Capuzzi, S, Elkins, J, Ettmayer, P, Frederiksen, M, Gileadi, O, Gray, N, Hooper, A, Knapp, S, Laufer, S, Luecking, U, Michaelides, M, Müller, S, Muratov, E, Denny, R, Saikatendu, K, Treiber, D, Zuercher, W, Willson, T
Format: Journal article
Language:English
Published: Public Library of Science 2017