LLT1 and CD161 expression in human germinal centers promotes B cell activation and CXCR4 downregulation
Germinal centers (GC) are microanatomical structures critical for the development of high-affinity antibodies and B-cell memory. They are organised into two zones, light and dark, with coordinated roles, controlled by local signalling. The innate Lectin-like transcript 1 (LLT1) is known to be expres...
Glavni autori: | Llibre, A, López-Macías, C, Marafioti, T, Mehta, H, Partridge, A, Kanzig, C, Rivellese, F, Galson, J, Walker, L, Milne, P, Phillips, R, Kelly, D, Freeman, G, El Shikh, M, Klenerman, P, Willberg, C |
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Format: | Journal article |
Izdano: |
American Association of Immunologists
2016
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