Interleukin-1 acts via the JNK-2 signaling pathway to induce aggrecan degradation by human chondrocytes
<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions"><strong>Objective: </strong>Aggrecan enables articular cartilage to bear load and resist compression. Aggrecan loss occurs early in osteoarthritis and rheumatoid arthritis and can be induced by inflammatory cytok...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2015
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