Interleukin-1 acts via the JNK-2 signaling pathway to induce aggrecan degradation by human chondrocytes
<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions"><strong>Objective: </strong>Aggrecan enables articular cartilage to bear load and resist compression. Aggrecan loss occurs early in osteoarthritis and rheumatoid arthritis and can be induced by inflammatory cytok...
Үндсэн зохиолчид: | Ismail, H, Yamamoto, K, Vincent, T, Nagase, H, Troeberg, L, Saklatvala, J |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Wiley
2015
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