Interleukin-1 acts via the JNK-2 signaling pathway to induce aggrecan degradation by human chondrocytes

<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions"><strong>Objective: </strong>Aggrecan enables articular cartilage to bear load and resist compression. Aggrecan loss occurs early in osteoarthritis and rheumatoid arthritis and can be induced by inflammatory cytok...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ismail, H, Yamamoto, K, Vincent, T, Nagase, H, Troeberg, L, Saklatvala, J
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Wiley 2015

Ижил төстэй зүйлс