Interleukin-1 acts via the JNK-2 signaling pathway to induce aggrecan degradation by human chondrocytes

Objective: Aggrecan enables articular cartilage to bear load and resist compression. Aggrecan loss occurs early in osteoarthritis and rheumatoid arthritis and can be induced by inflammatory cytok...

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Autors principals:	Ismail, H, Yamamoto, K, Vincent, T, Nagase, H, Troeberg, L, Saklatvala, J
Format:	Journal article
Idioma:	English
Publicat:	Wiley 2015

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