Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1 alpha localization in erythroblasts

Congenital dyserythropoietic anemia type 1 (CDA-1), a rare inborn anemia characterized by abnormal chromatin ultrastructure in erythroblasts, is caused by abnormalities in codanin-1, a highly conserved protein of unknown function. We have produced 3 monoclonal antibodies to codanin-1 that demonstrat...

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Bibliographic Details
Main Authors: Renella, R, Roberts, N, Brown, J, De Gobbi, M, Bird, L, Hassanali, T, Sharpe, J, Sloane-Stanley, J, Ferguson, D, Cordell, J, Buckle, V, Higgs, D, Wood, W
Format: Journal article
Language:English
Published: 2011