The role of the PB2 627-domain in influenza A virus polymerase function

The RNA genome of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase composed of the subunits PA, PB1 and PB2. High-resolution structural data revealed that the polymerase assembles into a central polymerase core and several auxiliary highly flexi...

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Detalhes bibliográficos
Principais autores: Nilsson, B, te Velthuis, A, Fodor, E
Formato: Journal article
Publicado em: American Society for Microbiology 2017