T cell selection during the evolution of CD8+ T cell memory in vivo.

Memory T cell responses are frequently highly restricted in terms of receptor usage. How and when such clonotypic dominance is established remains poorly understood. Here we have investigated the evolution of the T cell responses to an epitope from Epstein-Barr virus (EBV), (FLRGRAYGL), by analyzing...

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Detalles Bibliográficos
Main Authors: Callan, M, Annels, N, Steven, N, Tan, L, Wilson, J, Mcmichael, A, Rickinson, AB
Formato: Journal article
Idioma:English
Publicado: 1998