An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
A rostral brainstem structure, the pedunculopontine nucleus (PPN), is severely affected by Parkinson's disease (PD) pathology and is regarded a promising target for therapeutic deep-brain stimulation (DBS). However, understanding the PPN's role in PD and assessing the potential of DBS are...
Main Authors: | , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2015
|