An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.

A rostral brainstem structure, the pedunculopontine nucleus (PPN), is severely affected by Parkinson's disease (PD) pathology and is regarded a promising target for therapeutic deep-brain stimulation (DBS). However, understanding the PPN's role in PD and assessing the potential of DBS are...

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Bibliographic Details
Main Authors: Pienaar, I, Harrison, I, Elson, J, Bury, A, Woll, P, Simon, A, Dexter, D
Format: Journal article
Language:English
Published: 2015