An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.

A rostral brainstem structure, the pedunculopontine nucleus (PPN), is severely affected by Parkinson's disease (PD) pathology and is regarded a promising target for therapeutic deep-brain stimulation (DBS). However, understanding the PPN's role in PD and assessing the potential of DBS are...

Full description

Bibliographic Details
Main Authors:	Pienaar, I, Harrison, I, Elson, J, Bury, A, Woll, P, Simon, A, Dexter, D
Format:	Journal article
Language:	English
Published:	2015

Similar Items

Topographical organisation of non-cholinergic neurons in the pedunculopontine nucleus
by: Martínez González, C
Published: (2012)

Cholinergic input from the pedunculopontine nucleus to the cerebellum: implications for deep brain stimulation in Parkinson′s disease
by: Eugenio Scarnati, et al.
Published: (2016-01-01)

A Review of the Pedunculopontine Nucleus in Parkinson's Disease
by: Isobel T. French, et al.
Published: (2018-04-01)

Pedunculopontine Nucleus Degeneration Contributes to Both Motor and Non-Motor Symptoms of Parkinson’s Disease
by: Nicole Elaine Chambers, et al.
Published: (2020-01-01)

The pedunculopontine nucleus in Parkinson's disease: primate studies.
by: Nandi, D, et al.
Published: (2008)

Pedunculopontine nucleus.
by: Nandi, D, et al.
Published: (2004)

Functional connectivity of the pedunculopontine nucleus and surrounding region in parkinson’s disease
by: Brown, P, et al.
Published: (2016)

Pedunculopontine nucleus stimulation for gait and postural disorders in Parkinson's disease
by: Thevathasan, AW
Published: (2011)

Pedunculopontine nucleus stimulation improves gait freezing in Parkinson disease.
by: Thevathasan, W, et al.
Published: (2011)

What is the therapeutic mechanism of pedunculopontine nucleus stimulation in Parkinson's disease?
by: Wesley Thevathasan, et al.
Published: (2019-08-01)

Cholinergic Projections From the Pedunculopontine Tegmental Nucleus Contact Excitatory and Inhibitory Neurons in the Inferior Colliculus
by: William A. Noftz, et al.
Published: (2020-07-01)

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism
by: Thevathasan, W, et al.
Published: (2012)

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism.
by: Thevathasan, W, et al.
Published: (2012)

Microcircuits of the Pedunculopontine Nucleus
by: Mena-Segovia, J, et al.
Published: (2009)

Neurophysiology of the pedunculopontine tegmental nucleus
by: F. Vitale, et al.
Published: (2019-08-01)

Subpopulations of cholinergic, GABAergic and glutamatergic neurons in the pedunculopontine nucleus contain calcium-binding proteins and are heterogeneously distributed.
by: Martinez-Gonzalez, C, et al.
Published: (2012)

The Oxford Pedunculopontine Nucleus meeting.
by: Stein, J
Published: (2008)

Topographical organization of the pedunculopontine nucleus.
by: Martinez-Gonzalez, C, et al.
Published: (2011)

Divergent motor projections from the pedunculopontine nucleus are differentially regulated in Parkinsonism.
by: Martinez-Gonzalez, C, et al.
Published: (2014)

Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus.
by: Nandi, D, et al.
Published: (2002)

Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus
by: Nandi, D, et al.
Published: (2002)

Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review
by: Thevathasan, W, et al.
Published: (2017)

Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford.
by: Pereira, E, et al.
Published: (2008)

Pedunculopontine Nucleus Dysconnectivity Correlates With Gait Impairment in Parkinson’s Disease: An Exploratory Study
by: Stephen Joza, et al.
Published: (2022-07-01)

Pedunculopontine nucleus area oscillations during stance, stepping and freezing in Parkinson's disease.
by: Valerie Fraix, et al.
Published: (2013-01-01)

Pedunculopontine nucleus region deep brain stimulation in Parkinson disease: surgical anatomy and terminology
by: Hamani, C, et al.
Published: (2016)

The impact of low-frequency stimulation of the pedunculopontine nucleus region on reaction time in parkinsonism.
by: Thevathasan, W, et al.
Published: (2010)

Oscillations in Pedunculopontine Nucleus in Parkinson's disease and its relationship with deep brain stimulation
by: Min eLi, et al.
Published: (2015-09-01)

Pedunculopontine Nucleus [2] (multiple letters)
by: Nandi, D, et al.
Published: (2004)

Anatomy, physiology, and pathophysiology of the pedunculopontine nucleus.
by: Jenkinson, N, et al.
Published: (2009)

Lesions of cholinergic pedunculopontine tegmental nucleus neurons fail to affect cocaine or heroin self-administration or conditioned place preference in rats.
by: Stephan Steidl, et al.
Published: (2014-01-01)

Connectivity of the pedunculopontine nucleus in parkinsonian freezing of gait.
by: Schweder, P, et al.
Published: (2010)

The pedunculopontine region and breathing in Parkinson's disease
by: Jonathan A. Hyam, et al.
Published: (2019-05-01)

Walking exercise alters pedunculopontine nucleus connectivity in Parkinson’s disease in a dose-dependent manner
by: Jiayue Cai, et al.
Published: (2022-08-01)

7.0T ultrahigh-field MRI directly visualized the pedunculopontine nucleus in Parkinson’s disease patients
by: Jia-Wei Wang, et al.
Published: (2019-04-01)

The effects of deep brain stimulation of the pedunculopontine nucleus on cognition in Parkinson's disease and Progressive Supranuclear Palsy
by: Friederike Leimbach, et al.
Published: (2019-01-01)

The pedunculopontine nucleus: From posture and locomotion to neuroepigenetics
by: T. Virmani, et al.
Published: (2019-09-01)

The pedunculopontine region and breathing in Parkinson's disease
by: Hyam, JA, et al.
Published: (2019)

Chronic pedunculopontine nucleus stimulation restores functional connectivity.
by: Schweder, P, et al.
Published: (2010)

Towards a computational model for stimulation of the Pedunculopontine nucleus
by: Heida Tjitske, et al.
Published: (2009-07-01)