Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies.

The nuclear lamina provides structural support to the nucleus and has a central role in nuclear organization and gene regulation. Defects in its constituents, the lamins, lead to a class of genetic diseases collectively referred to as laminopathies. Using live cell imaging, we observed the occurrenc...

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Bibliographic Details
Main Authors: De Vos, W, Houben, F, Kamps, M, Malhas, A, Verheyen, F, Cox, J, Manders, E, Verstraeten, V, Steensel, v, Marcelis, C, van den Wijngaard, A, Vaux, D, Ramaekers, F, Broers, J
Format: Journal article
Language:English
Published: 2011