Enhancing the efficacy of viral vector blood-stage malaria vaccines

Enhancing the efficacy of viral vector blood-stage malaria vaccines

<p>Replication-deficient adenovirus (Ad) and modified vaccinia virus Ankara (MVA) vectors expressing single Plasmodium falciparum antigens can induce potent T cell and antibody responses and have entered clinical testing using a heterologous prime-boost immunisation approach (Ad_MVA). This the...

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Bibliografiske detaljer
Hovedforfatter:	Forbes, E
Andre forfattere:	Hill, A
Format:	Thesis
Sprog:	English
Udgivet:	2011
Fag:	Clinical laboratory sciences Malaria Immunology Vaccinology Parasitology Infectious diseases

Lignende værker

Pre-clinical development of viral vectored transmission-blocking malaria vaccines
af: Kapulu, MC
Udgivet: (2014)

Developing novel blood-stage malaria vaccines
af: Douglas, AD
Udgivet: (2015)

Malaria pre-erythrocytic stage vaccines: targeting antigen combinations
af: Bauza, K
Udgivet: (2012)

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors
af: de Cassan, S
Udgivet: (2011)

Analysis of b cell responses to blood-stage malaria antigens in humans following immunization with candidate vaccines and controlled human malaria infection
af: Elias, SC
Udgivet: (2014)

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches
af: Pearson, FE
Udgivet: (2011)

Liver-stage vaccines for malaria
af: Longley, RJ
Udgivet: (2013)

Long term efficacy of a pre-erythrocytic malaria vaccine and correlates of protection in children residing in a malaria endemic country
af: Olotu, A
Udgivet: (2013)

Hepcidin regulation in Malaria
af: Spottiswoode, N
Udgivet: (2015)

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
af: Antrobus, R
Udgivet: (2014)

The role of antigen in the maintenance and localisation of CD8+ T-cells in the context of liver stage malaria
af: Gola, A
Udgivet: (2018)

Biodegradable pulsatile release technologies for viral vector based vaccinations
af: Krastev, C
Udgivet: (2018)

New approaches for improving the immunogenicity of modified vaccinia virus Ankara as a recombinant vaccine vector
af: Alharbi, N
Udgivet: (2014)

A simplified 4-site economical intradermal post-exposure rabies vaccine regimen: a randomised controlled comparison with standard methods
af: Warrell, M, et al.
Udgivet: (2008)

Novel adenoviral vectored vaccines and the implications of viral diversity in therapeutic strategies against Hepatitis C Virus infection
af: Kelly, C
Udgivet: (2013)

B cell responses to conjugate and polysaccharide meningococcal vaccines
af: Ramasamy, M
Udgivet: (2012)

Development of antimalarial human monoclonal antibodies against Plasmodium falciparum
af: Wang, LT
Udgivet: (2022)

Evaluation of the immunological mechanisms induced by mycobacteria and the potential effect this may have on immunity induced by tuberculosis vaccines
af: Poyntz, HC
Udgivet: (2012)

Towards the development of multi-disease vaccines against arthropod-borne viruses
af: Montalvo Zurbía Flores, G
Udgivet: (2022)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
af: Hennig, B, et al.
Udgivet: (2008)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
af: Harris, S, et al.
Udgivet: (2013)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
af: Ronan, E
Udgivet: (2011)

Evaluation of the immunogenicity of a promising vaccine regimen to identify immune correlates of protection
af: Pinpathomrat, N
Udgivet: (2018)

Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
af: Griffiths, K
Udgivet: (2012)

CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
af: Emilie Pollenus, et al.
Udgivet: (2021-02-01)

Corrigendum: CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
af: Emilie Pollenus, et al.
Udgivet: (2022-06-01)

Control of typhoid fever: evaluating herd protection through public health use of typhoid VI polysaccharide vaccine
af: Ochiai, R
Udgivet: (2011)

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
af: Matsumiya, M, et al.
Udgivet: (2014)

Innate immune responses to tuberculosis vaccines
af: Matsumiya, M
Udgivet: (2014)

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
af: Wong, S
Udgivet: (2013)

T Helper Plasticity Is Orchestrated by STAT3, Bcl6, and Blimp-1 Balancing Pathology and Protection in Malaria
af: Victor H. Carpio, et al.
Udgivet: (2020-07-01)

Effect of needle size on immunogenicity and reactogenicity of vaccines in infants: randomised controlled trial
af: Diggle, L, et al.
Udgivet: (2006)

Effect of hemoglobins S and C on the in vivo expression and immune recognition of Plasmodium falciparum erythrocyte membrane protein 1 variants in Malian children
af: Beaudry, J
Udgivet: (2012)

Characterisation of T cells induced by candidate conserved region HIV-1 vaccines in healthy HIV-1/2 negative volunteers
af: Ahmed, T, et al.
Udgivet: (2014)

The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine
af: Clutterbuck, E, et al.
Udgivet: (2006)

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection
af: Ying Du, et al.
Udgivet: (2020-04-01)

Comparison of a limiting dilution assay and ELISpot for detection of memory B-cells before and after immunisation with a protein-polysaccharide conjugate vaccine in children
af: Blanchard-Rohner, G, et al.
Udgivet: (2010)

NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment
af: Emilie Pollenus, et al.
Udgivet: (2024-09-01)

Discovery of a conserved Plasmodium antigen on the surface of malaria-infected red blood cells
af: Oteng, EK
Udgivet: (2013)

Evaluation of immune correlates to TB vaccines
af: Marsay, L
Udgivet: (2011)