The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

ver descrição completa

Detalhes bibliográficos
Principais autores:	Fearnhead, N, Britton, M, Bodmer, W
Formato:	Journal article
Idioma:	English
Publicado em:	2001

Registros relacionados

Familial adenomatous polyposis (FAP) and its gene, APC.
por: Bodmer, W
Publicado em: (1999)

APC in the regulation of intestinal crypt fission.
por: Wasan, H, et al.
Publicado em: (1998)

PHYSICAL MAPPING OF THE APC REGION
por: Thomas, H, et al.
Publicado em: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
por: Cottrell, S, et al.
Publicado em: (1992)

ABC of smoking cessation /
por: Britton, John
Publicado em: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
por: Lamlum, H, et al.
Publicado em: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
por: Homfray, T, et al.
Publicado em: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
por: Fearnhead, N, et al.
Publicado em: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
por: Fearnhead, N, et al.
Publicado em: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
por: Anna Höfler, et al.
Publicado em: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
por: Mehrnaz Ghazvini, et al.
Publicado em: (2013-01-01)

APC and the three-hit hypothesis.
por: Segditsas, S, et al.
Publicado em: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
por: Haines, J, et al.
Publicado em: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
por: Rowan, A, et al.
Publicado em: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
por: Sieber, O, et al.
Publicado em: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
por: Höfler, A, et al.
Publicado em: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
por: Lauren E. King, et al.
Publicado em: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
por: Felix, R, et al.
Publicado em: (2003)

Sharing the happiness of receiving APC
por: Siti Nur Azwin, Zulkapri
Publicado em: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
por: Sarah Darling, et al.
Publicado em: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
por: Coffey Robert J, et al.
Publicado em: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
por: Lefevre, J, et al.
Publicado em: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
por: Schneikert, Jean, et al.
Publicado em: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
por: Jean Schneikert, et al.
Publicado em: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
por: Stanislau Yatskevich, et al.
Publicado em: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
por: Blancheteau, V, et al.
Publicado em: (2001)

APC-Verwaltung im institutionellen Repositorium
por: Wagner, Alexander
Publicado em: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
por: Dimitriya H. Garvanska, et al.
Publicado em: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
por: Fearnhead, N, et al.
Publicado em: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
por: Xingyuan Fang, et al.
Publicado em: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
por: Harvey, J, et al.
Publicado em: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
por: Lamlum, H, et al.
Publicado em: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
por: Frayling, I, et al.
Publicado em: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
por: Austin M. Gabel, et al.
Publicado em: (2024-10-01)

ABC of AIDS /
por: Adler, Michael W.
Publicado em: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
por: Deheragoda, MG, et al.
Publicado em: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
por: Hitchins, M, et al.
Publicado em: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
por: Nagy Olga, et al.
Publicado em: (2012-03-01)

326 warga UUM terima penghargaan APC
por: Utusan, Malaysia
Publicado em: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
por: MPRC, Pusat Media & Perhubungan Awam
Publicado em: (2017)