The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

Полное описание

Библиографические подробности
Главные авторы:	Fearnhead, N, Britton, M, Bodmer, W
Формат:	Journal article
Язык:	English
Опубликовано:	2001

Схожие документы

Familial adenomatous polyposis (FAP) and its gene, APC.
по: Bodmer, W
Опубликовано: (1999)

APC in the regulation of intestinal crypt fission.
по: Wasan, H, и др.
Опубликовано: (1998)

PHYSICAL MAPPING OF THE APC REGION
по: Thomas, H, и др.
Опубликовано: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
по: Cottrell, S, и др.
Опубликовано: (1992)

ABC of smoking cessation /
по: Britton, John
Опубликовано: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
по: Lamlum, H, и др.
Опубликовано: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
по: Homfray, T, и др.
Опубликовано: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
по: Fearnhead, N, и др.
Опубликовано: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
по: Fearnhead, N, и др.
Опубликовано: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
по: Anna Höfler, и др.
Опубликовано: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
по: Mehrnaz Ghazvini, и др.
Опубликовано: (2013-01-01)

APC and the three-hit hypothesis.
по: Segditsas, S, и др.
Опубликовано: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
по: Haines, J, и др.
Опубликовано: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
по: Rowan, A, и др.
Опубликовано: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
по: Sieber, O, и др.
Опубликовано: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
по: Höfler, A, и др.
Опубликовано: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
по: Lauren E. King, и др.
Опубликовано: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
по: Felix, R, и др.
Опубликовано: (2003)

Sharing the happiness of receiving APC
по: Siti Nur Azwin, Zulkapri
Опубликовано: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
по: Sarah Darling, и др.
Опубликовано: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
по: Coffey Robert J, и др.
Опубликовано: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
по: Lefevre, J, и др.
Опубликовано: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
по: Schneikert, Jean, и др.
Опубликовано: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
по: Jean Schneikert, и др.
Опубликовано: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
по: Stanislau Yatskevich, и др.
Опубликовано: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
по: Blancheteau, V, и др.
Опубликовано: (2001)

APC-Verwaltung im institutionellen Repositorium
по: Wagner, Alexander
Опубликовано: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
по: Dimitriya H. Garvanska, и др.
Опубликовано: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
по: Fearnhead, N, и др.
Опубликовано: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
по: Xingyuan Fang, и др.
Опубликовано: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
по: Harvey, J, и др.
Опубликовано: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
по: Lamlum, H, и др.
Опубликовано: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
по: Frayling, I, и др.
Опубликовано: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
по: Austin M. Gabel, и др.
Опубликовано: (2024-10-01)

ABC of AIDS /
по: Adler, Michael W.
Опубликовано: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
по: Deheragoda, MG, и др.
Опубликовано: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
по: Hitchins, M, и др.
Опубликовано: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
по: Nagy Olga, и др.
Опубликовано: (2012-03-01)

326 warga UUM terima penghargaan APC
по: Utusan, Malaysia
Опубликовано: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
по: MPRC, Pusat Media & Perhubungan Awam
Опубликовано: (2017)