Stable recombination hotspots in birds

The DNA-binding protein PRDM9 has a critical role in specifying meiotic recombination hotspots in mice and apes, but it appears to be absent from other vertebrate species, including birds. To study the evolution and determinants of recombination in species lacking the gene that encodes PRDM9, we inf...

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Main Authors: Singhal, S, Leffler, E, Sannareddy, K, Turner, I, Venn, O, Hooper, D, Strand, A, Li, Q, Raney, B, Balakrishnan, C, Griffith, S, McVean, G, Przeworski, M
格式: Journal article
出版: American Association for the Advancement of Science 2015