Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

عرض إصدارات أخرى (1)

Two members of the human aldo-keto reductase (AKR) superfamily participate in the biosynthesis of bile acids by catalyzing the NADP(H) dependent reduction of 3-keto groups (AKR1C4) and Delta4 double bonds (AKR1D1) of oxysterol precursors. Structure determination of human AKR1C4 and homology modellin...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lee, W, Lukacik, P, Guo, K, Ugochukwu, E, Kavanagh, K, Marsden, B, Oppermann, U
التنسيق: Journal article
اللغة:English
منشور في: 2009
الموضوعات:
biosynthesis
Tryptophan
Crystallography, X-Ray
Structural Homology, Protein
Humans
Catalytic Domain
metabolism
Oxidoreductases
Ligands
Models, Molecular
chemistry
Structure-Activity Relationship
Bile Acids and Salts
عرض كل الإصدارات (2)

مواد مشابهة