Mechanistic investigation of Rh(i)-catalysedasymmetric Suzuki–Miyaura coupling withracemic allyl halides

Understanding how catalytic asymmetric reactions with racemic starting materials can operate would enable new enantioselective cross-coupling reactions that give chiral products. Here we propose a catalytic cycle for the highly enantioselective Rh(I)-catalysed Suzuki–Miyaura coupling of boronic acid...

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Bibliographic Details
Main Authors: Van Dijk, LL, Ardkhean, R, Sidera, M, Karabiyikoglu, S, Sari, Ö, Claridge, T, Lloyd-Jones, G, Paton, R, Fletcher, S
Format: Journal article
Language:English
Published: Nature 2021