Dengue in Vietnamese infants--results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity.

The pathogenesis of severe dengue is not well understood. Maternally derived subneutralizing levels of dengue virus-reactive IgG are postulated to be a critical risk factor for severe dengue during infancy. In this study, we found that, in healthy Vietnamese infants, there was a strong temporal asso...

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Bibliographic Details
Main Authors: Chau, T, Quyen, N, Thuy, T, Tuan, N, Hoang, D, Dung, N, Lien, L, Quy, N, Hieu, N, Hieu, LT, Hien, T, Hung, N, Farrar, J, Simmons, C
Format: Journal article
Language:English
Published: 2008