Empty MHC class I molecules come out in the cold.

Major histocompatibility complex (MHC) class I molecules present antigen by transporting peptides from intracellularly degraded proteins to the cell surface for scrutiny by cytotoxic T cells. Recent work suggests that peptide binding may be required for efficient assembly and intracellular transport...

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Bibliographic Details
Main Authors: Ljunggren, H, Stam, N, Ohlén, C, Neefjes, J, Höglund, P, Heemels, M, Bastin, J, Schumacher, T, Townsend, A, Kärre, K
Format: Journal article
Language:English
Published: 1990