Empty MHC class I molecules come out in the cold.
Major histocompatibility complex (MHC) class I molecules present antigen by transporting peptides from intracellularly degraded proteins to the cell surface for scrutiny by cytotoxic T cells. Recent work suggests that peptide binding may be required for efficient assembly and intracellular transport...
Главные авторы: | Ljunggren, H, Stam, N, Ohlén, C, Neefjes, J, Höglund, P, Heemels, M, Bastin, J, Schumacher, T, Townsend, A, Kärre, K |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
1990
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