Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity.

Natural regulatory T cells (T(reg)) represent a distinct lineage of T lymphocytes committed to suppressive functions, and expression of the transcription factor Foxp3 is thought to identify this lineage specifically. Here we report that, whereas the majority of natural CD4(+)Foxp3(+) T cells maintai...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Komatsu, N, Mariotti-Ferrandiz, M, Wang, Y, Malissen, B, Waldmann, H, Hori, S
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2009