Antibody response to dietary and autoantigens in G alpha i2-deficient mice.
BACKGROUND: Mice with a targeted mutation in the G protein subunit G alpha i2 gene develop a colonic mucosal inflammation, with a highly activated B-cell response. We wanted to investigate whether this increased B-cell activity was directed against dietary antigens and/or various self tissues. METH...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2001
|