OnPLS-based multi-block data integration: a multivariate approach to interrogating biological interactions in asthma

Integration of multiomics data remains a key challenge in fulfilling the potential of comprehensive systems biology. Multiple-block orthogonal projections to latent structures (OnPLS) is a projection method that simultaneously models multiple data matrices, reducing feature space without relying on...

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Bibliographic Details
Main Authors: Reinke, SN, Galindo-Prieto, B, Skotare, T, Broadhurst, DI, Singhania, A, Horowitz, D, Djukanovic, R, Hinks, TSC, Geladi, P, Trygg, J, Wheelock, CE
Format: Journal article
Language:English
Published: American Chemical Society 2018