Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III.

RNA polymerases are essential enzymes which transcribe DNA into RNA. Here, we obtain mass spectra of the cellular forms of apo and holo eukaryotic RNA polymerase I and III, defining their composition under different solution conditions. By recombinant expression of subunits within the initiation het...

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Detalles Bibliográficos
Autores principales: Lane, L, Fernández-Tornero, C, Zhou, M, Morgner, N, Ptchelkine, D, Steuerwald, U, Politis, A, Lindner, D, Gvozdenovic, J, Gavin, A, Müller, C, Robinson, C
Formato: Journal article
Lenguaje:English
Publicado: 2011