Accurate Computation of Likelihoods in the Coalescent with Recombination via Parsimony.

Accurate Computation of Likelihoods in the Coalescent with Recombination via Parsimony.

Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of applications. A widely-used method of estimating recombination rates is the maximum likelihood approach, and the problem of...

Полное описание

Библиографические подробности
Главные авторы:	Lyngsø, R, Song, Y, Hein, J
Формат:	Journal article
Язык:	English
Опубликовано:	2008

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