Accurate Computation of Likelihoods in the Coalescent with Recombination via Parsimony.

Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of applications. A widely-used method of estimating recombination rates is the maximum likelihood approach, and the problem of...

詳細記述

書誌詳細
主要な著者: Lyngsø, R, Song, Y, Hein, J
フォーマット: Journal article
言語:English
出版事項: 2008