Coefficient of failure: a methodology for examining longitudinal beta-cell function in Type 2 diabetes.

AIMS: We describe a new method, the determination of the coefficient of failure, which allows the assessment of beta-cell failure from any index of glycaemia. Previous methods using glycaemic thresholds and calculating time-to-failure have systematic deficiencies relating to bias, reproducibility an...

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Bibliographic Details
Main Authors: Wallace, T, Matthews, DR
Format: Journal article
Language:English
Published: 2002