FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth.

Progression of prostate cancer is highly dependent upon the androgen receptor pathway, such that knowledge of androgen-regulated proteins is vital to understand and combat this disease. Using a proteomic screen, we found the RNA-binding protein FUS/TLS (Fused in Ewing's Sarcoma/Translocated in...

Full description

Bibliographic Details
Main Authors: Brooke, G, Culley, R, Dart, D, Mann, D, Gaughan, L, McCracken, SR, Robson, C, Spencer-Dene, B, Gamble, S, Powell, S, Wait, R, Waxman, J, Walker, M, Bevan, C
Format: Journal article
Language:English
Published: 2011