Membrane binding of antimicrobial peptides is modulated by lipid charge modification

Peptide interactions with lipid bilayers play a key role in a range of biological processes and depend on electrostatic interactions between charged amino acids and lipid headgroups. Antimicrobial peptides (AMPs) initiate the killing of bacteria by binding to and destabilizing their membranes. The m...

Full description

Bibliographic Details
Main Authors: Simcock, P, Bublitz, M, Cipcigan, F, Stansfeld, P, Crain, J, Ryadnov, MG, Sansom, MSP
Format: Journal article
Language:English
Published: American Chemical Society 2021