Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function-associated antigen 3.
LFA-3 was purified with an intact (mLFA-3) or an enzymatically removed membrane-anchoring domain (sLFA-3). Gel filtration and sucrose gradient sedimentation showed sLFA-3 to be a single highly glycosylated polypeptide chain in solution, while mLFA-3 formed micelles of 8 LFA-3 monomers. 125I-mLFA-3 b...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1989
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