Models of defective insulin secretion in human and mouse pancreatic islets: impact of granule exocytosis, mitochondrial metabolism, and ageing

<p>Type-2 diabetes (T2D), a multi-factorial disease characterised by chronic hyperglycaemia, is caused by a complex interaction between genetic and environmental factors. Genetic and phenotypic characterisations of diabetic patients suggest that a combination of β-cell failure, culminating in...

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Detaylı Bibliyografya
Yazar: Do, HW
Diğer Yazarlar: Rorsman, P
Materyal Türü: Tez
Dil:English
Baskı/Yayın Bilgisi: 2015
Konular: