Models of defective insulin secretion in human and mouse pancreatic islets: impact of granule exocytosis, mitochondrial metabolism, and ageing
<p>Type-2 diabetes (T2D), a multi-factorial disease characterised by chronic hyperglycaemia, is caused by a complex interaction between genetic and environmental factors. Genetic and phenotypic characterisations of diabetic patients suggest that a combination of β-cell failure, culminating in...
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| Format: | Thesis |
| Language: | English |
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2015
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