F-actin-driven CD28-CD80 localization in the immune synapse

During immunological synapse (IS) formation, T cell receptor (TCR) signaling complexes, integrins, and costimulatory molecules exhibit a particular spatial localization. Here, we develop an agent-based model for the IS formation based on TCR peptide-bound major histocompatibility complex (pMHC) and...

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書目詳細資料
Main Authors: Siokis, A, Robert, P, Demetriou, P, Dustin, M, Meyer-Hermann, M
格式: Journal article
語言:English
出版: Elsevier 2018