F-actin-driven CD28-CD80 localization in the immune synapse

F-actin-driven CD28-CD80 localization in the immune synapse

Show other versions (1)

During immunological synapse (IS) formation, T cell receptor (TCR) signaling complexes, integrins, and costimulatory molecules exhibit a particular spatial localization. Here, we develop an agent-based model for the IS formation based on TCR peptide-bound major histocompatibility complex (pMHC) and...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Siokis, A, Robert, P, Demetriou, P, Dustin, M, Meyer-Hermann, M
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 2018

Lignende værker

F-actin driven CD28-CD80 localization in the Immune Synapse
af: Meyer-Hermann, M, et al.
Udgivet: (2018)

The immunological synapse and CD28-CD80 interactions.
af: Bromley, S, et al.
Udgivet: (2001)

CD28-CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation.
af: Thauland, T, et al.
Udgivet: (2014)

CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse.
af: Tseng, S, et al.
Udgivet: (2005)

Characterization of mechanisms positioning costimulatory complexes in immune synapses
af: Siokis, A, et al.
Udgivet: (2021)

T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta.
af: Tseng, S, et al.
Udgivet: (2008)

Characterization of mechanisms positioning costimulatory complexes in immune synapses
af: Anastasios Siokis, et al.
Udgivet: (2021-10-01)

A dynamic CD2 rich compartment at the outer edge of the immunological synapse boosts and integrates signals
af: Demetriou, P, et al.
Udgivet: (2020)

Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses.
af: Dustin, M
Udgivet: (2007)

P07-03. HIV gp120 interaction with CD4+ T cells induces local intracellular signaling and creates an F-actin depleted zone in the virological synapse
af: Vasiliver-Shamis, G, et al.
Udgivet: (2009)

Actin cytoskeleton and the dynamics of immunological synapse
af: Mayya, V, et al.
Udgivet: (2010)

CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse
af: Barbara Molon, et al.
Udgivet: (2022-08-01)

The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses.
af: McCann, F, et al.
Udgivet: (2003)

Clinical Significance of BTLA, CD27, CD70, CD28 and CD80 as Diagnostic and Prognostic Markers in Ovarian Cancer
af: Janina Świderska, et al.
Udgivet: (2022-01-01)

Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells
af: Dilek Nahzli, et al.
Udgivet: (2012-11-01)

Modulation of Regulatory T Cells Activity by Distinct CD80 and CD86 Interactions With CD28/CTLA-4 in Chagas Cardiomyopathy
af: Bruna F. Pinto, et al.
Udgivet: (2022-05-01)

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity
af: Mark F. Maurer, et al.
Udgivet: (2022-04-01)

Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.
af: Hailman, E, et al.
Udgivet: (2002)

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.
af: Dustin, M, et al.
Udgivet: (2000)

sCD163, sCD28, sCD80, and sCTLA-4 as soluble marker candidates for detecting immunosenescence
af: Andrea Aprilia, et al.
Udgivet: (2024-01-01)

The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas
af: Luka de Vos, et al.
Udgivet: (2020-11-01)

Costimulatory blockade of the CD28 / CD80-86 / CTLA-4 balance in transplantation: impact on memory T cells?
af: Simon eVille, et al.
Udgivet: (2015-08-01)

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics.
af: van der Merwe, P, et al.
Udgivet: (1997)

Soluble CD83 Regulates Dendritic Cell–T Cell Immunological Synapse Formation by Disrupting Rab1a-Mediated F-Actin Rearrangement
af: Wei Lin, et al.
Udgivet: (2021-01-01)

Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse.
af: Milstein, O, et al.
Udgivet: (2008)

Chimeric CTLA4-CD28-CD3z T Cells Potentiate Antitumor Activity Against CD80/CD86–Positive B Cell Malignancies
af: Shouheng Lin, et al.
Udgivet: (2021-04-01)

The CD58-CD2 axis in cancer immune evasion
af: Quastel, M, et al.
Udgivet: (2022)

Phospholipids: Pulling Back the Actin Curtain for Granule Delivery to the Immune Synapse
af: Christian M. Gawden-Bone, et al.
Udgivet: (2019-04-01)

CD28 Aptamers as Powerful Immune Response Modulators
af: Fernando Pastor, et al.
Udgivet: (2013-01-01)

Actin Dynamics at the T Cell Synapse as Revealed by Immune-Related Actinopathies
af: Loïc Dupré, et al.
Udgivet: (2021-06-01)

Signaling at neuro/immune synapses.
af: Dustin, M
Udgivet: (2012)

Molecular and Functional Analyses of the Primordial Costimulatory Molecule CD80/86 and Its Receptors CD28 and CD152 (CTLA-4) in a Teleost Fish
af: Tao-Zhen Lu, et al.
Udgivet: (2022-06-01)

Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility.
af: Bashour, K, et al.
Udgivet: (2014)

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
af: Yannick D. Muller, et al.
Udgivet: (2021-03-01)

The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis
af: Weixi Liu, et al.
Udgivet: (2021-02-01)

CD80 expression promotes immune surveillance in Barrett’s metaplasia
af: Melania Scarpa, et al.
Udgivet: (2019-10-01)

The value of changes in CD8+CD28+ and CD4+CD28+ cells in patients with HIV infection concurrent with tuberculosis during treatment
af: A A Popova, et al.
Udgivet: (2013-11-01)

Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.
af: Nahzli Dilek, et al.
Udgivet: (2013-01-01)

Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recovery of CD27, CD28, CD40, CD80, ICOS and GITR and substantially increased levels of PD-L1, LAG-3 and TIM-3
af: Bernardo L. Rapoport, et al.
Udgivet: (2023-03-01)

Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes
af: Judith Pineau, et al.
Udgivet: (2022-09-01)