F-actin-driven CD28-CD80 localization in the immune synapse

F-actin-driven CD28-CD80 localization in the immune synapse

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During immunological synapse (IS) formation, T cell receptor (TCR) signaling complexes, integrins, and costimulatory molecules exhibit a particular spatial localization. Here, we develop an agent-based model for the IS formation based on TCR peptide-bound major histocompatibility complex (pMHC) and...

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Bibliographische Detailangaben
Hauptverfasser:	Siokis, A, Robert, P, Demetriou, P, Dustin, M, Meyer-Hermann, M
Format:	Journal article
Sprache:	English
Veröffentlicht:	Elsevier 2018

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