Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: an emergent therapeutic target

Tuberculosis (TB) is the leading cause of death from a single infectious agent and in 2019 an estimated 10 million people worldwide contracted the disease. Although treatments for TB exist, continual emergence of drug-resistant variants necessitates urgent development of novel antituberculars. An im...

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Bibliographic Details
Main Authors: Adams, O, Deme, JC, Parker, JL, Fowler, PW, Lea, SM, Newstead, S
Other Authors: CRyPTIC Consortium
Format: Journal article
Language:English
Published: Elsevier 2021