Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue

Emissive base analogs are powerful tools for probing nucleic acids at the molecular level. Herein we describe the development and thorough characterization of pentacyclic adenine (pA), a versatile base analog with exceptional fluorescence properties. When incorporated into DNA, pA pairs selectively...

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Bibliographic Details
Main Authors: Bood, M, Füchtbauer, AF, Wranne, MS, Ro, JJ, Sarangamath, S, El-Sagheer, AH, Rupert, DLM, Fisher, RS, Magennis, SW, Jones, AC, Höök, F, Brown, T, Kim, BH, Dahlén, A, Wilhelmsson, LM, Grøtli, M
Format: Journal article
Published: Royal Society of Chemistry 2018