Detergent-free Lipodisq nanoparticles facilitate high-resolution mass spectrometry of folded integral membrane proteins

Integral membrane proteins pose considerable challenges to mass spectrometry (MS) owing to the complexity and diversity of the components in their native environment. Here, we use native MS to study the post-translational maturation of bacteriorhodopsin (bR) and archaerhodopsin-3 (AR3), using both o...

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Bibliographic Details
Main Authors: Hoi, KK, Bada Juarez, JF, Judge, PJ, Yen, H-Y, Wu, D, Vinals, J, Taylor, GF, Watts, A, Robinson, CV
Format: Journal article
Language:English
Published: American Chemical Society 2021