The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding.

The structure of murine leukemia inhibitory factor (LIF) has been determined by X-ray crystallography at 2.0 A resolution. The main chain fold conforms to the four alpha-helix bundle topology previously observed for several members of the hematopoietic cytokine family. Of these, LIF shows closest st...

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Bibliographic Details
Main Authors: Robinson, R, Grey, L, Staunton, D, Vankelecom, H, Vernallis, AB, Moreau, J, Stuart, D, Heath, J, Jones, E
Format: Journal article
Language:English
Published: 1994