Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens.

Protection against mucosally transmitted infections probably requires immunity at the site of pathogen entry, yet there are no mucosal adjuvant formulations licensed for human use. Polyethyleneimine (PEI) represents a family of organic polycations used as nucleic acid transfection reagents in vitro...

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Bibliographic Details
Main Authors: Wegmann, F, Gartlan, K, Harandi, A, Brinckmann, SA, Coccia, M, Hillson, W, Kok, W, Cole, S, Ho, L, Lambe, T, Puthia, M, Svanborg, C, Scherer, E, Krashias, G, Williams, A, Blattman, J, Greenberg, P, Flavell, R, Moghaddam, A, Sheppard, N, Sattentau, Q
Format: Journal article
Language:English
Published: 2012