Jekyll and Hyde: the transformation of HLA-B27.
HLA-B27 can adopt a homodimeric form. In spondyloarthritis, such aberrant expression of B27 may override a tissue-specific inhibition of major histocompatibility complex (MHC) class I-dependent events, leading to inflammation and fibrosis.
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2000
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