Mutations in the chromatin-associated protein ATRX.

ATRX belongs to the SNF2 family of proteins, many of which have been demonstrated to have chromatin remodeling activity. Constitution mutations in the X-encoded gene give rise to alpha thalassemia mental retardation (ATR-X) syndrome and a variety of related conditions that are often associated with...

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Main Authors: Gibbons, R, Wada, T, Fisher, C, Malik, N, Mitson, M, Steensma, D, Fryer, A, Goudie, DR, Krantz, I, Traeger-Synodinos, J
格式: Journal article
语言:English
出版: 2008